Take cold medicine and kidney failure! Class 3 drugs easy to acute urinary retention serious fear of kidney washing 1 precursor need to be careful

Winter hard to avoid cold, take cold medicine to pay special attention to urination, part of the drug may cause “acute urinary retention”, serious words can damage the kidney. Last month, a 91-year-old man took cold medicine for several days and developed urinary retention and kidney failure.

This old man, take cold medicine more severe abdominal distension, two days can’t eat in the future, family depends not hurriedly brought him for medical treatment, the results computed tomography (ct) reflect his bladder is as big as grapefruit and oppression to the stomach and intestines, and blood creatinine acid index soared, according to a report diagnosed with acute renal failure caused by acute urinary retention, physician hurriedly to the old man placed the urine tube, drainage gives more than 1 liter of urine, a few days to recover the kidney function.

Urinary retention can seriously damage the kidneys

According to the health education information of The Affiliated Hospital of Asian University, about 10% of the cases of acute urinary retention are caused by drugs, and such cases tend to occur in the elderly, because most of the elderly need to take a variety of acute and chronic drugs, so the risk of occurrence is high.

Among all kinds of drugs, the case of acute urinary retention caused by antihistamine in cold medicine is the most common one. For example, some components of the first generation of antihistamine will make the bladder muscles unable to contract, resulting in the inability to urinate in patients with excessive pressure at the bladder outlet, resulting in acute urinary retention. In addition, pseudoephedrine, used in cold medicines to relieve symptoms of runny nose, can also cause bladder neck muscles to tighten, making it more likely that pseudoephedrine will cause urinary retention if you have an enlarged prostate gland.

Patients with acute urinary retention often experience the feeling of “wanting to urinate but not being able to urinate.” In severe cases, the bladder can swell to its limit, pressing on the stomach and small intestine, making it impossible to eat, and even causing kidney injury. If urine remains too long without timely treatment, it may lead to irreversible chronic kidney damage, and in severe cases, short-term kidney washing is even required.

According to the Shutian Urology eye Clinic website, the risk factors for acute urinary retention are:


The older you are, the more likely you are to be over 40.

Acute urinary retention has occurred.

Bladder outlet obstruction, such as prostatic hypertrophy, bladder calculi, urethral stricture, and tumor, are all possible causes.

Take medication.

To recover from a surgical anaesthesia, or to use a painkiller (morphine).

Take diuretic drugs or drinks, such as diuretics, beer, tea, coffee, etc.

People with abnormal increase in urine output. There may be a blockage in the urethra, a bladder diverticulum, or a lack of bladder contractility.

Urinary retention typically occurs in older men, especially those with enlarged prostate glands that can block bladder exits, but it can also occur in younger people, including a 13-year-old student who developed acute urinary retention last year from taking cold medications.

  1. Drugs easily lead to acute urinary retention, prostatic hypertrophy or precursors of hypertrophy should be careful

Taipei city hospital medical physician Zheng Jiehao said, will cause the urine drug, with people often buy medicine, medicine is given priority to, such as:

Antihistamines (used to relieve skin itching and runny nose) such as Diphenhydramine, hydroxyzine, chlorpheniramine, etc.

Pseudoephedrine (pseudoephedrine) a sympathetic receptor pseudoephedrine (pseudoephedrine), commonly used to reduce nasal congestion and relieve nasal congestion.

The drug used to treat frequent urination, manic “antiacetylcholine.”

Prevention of acute urinary retention in addition to the careful use of drugs, Zheng Jiehao doctor reminds, including added moisture, not a full bladder, weight control, eating more fruits and vegetables, etc., is a prevention focus. If you have a history of prostatic hypertrophy, you must be careful when using the drugs mentioned above. If you have any problems with urine solution, do not hesitate to seek medical advice, and seek medical examination as soon as possible to avoid worsening of the condition.