Summer night chagrin hot, orange drink in the chair can no longer sit, holding the knees buried head to the floor, we are on the side of the mouth to ask: “want to sea king gold bottle?” “Want chicken essence?” She shook her head and said in clear words, “It’s all placebo.” We continued to rack our brains, “Milk?” “Do you want bread?” She shook her head again and replied firmly, “That only works if you drink it before you drink.”
It was eloquently proven that while the ethanol had paralyzed Orange’s cerebellum, her brain was definitely still running at high speed. A 2005 study in the British Medical Journal summarized various “remedies” and “antidotes” for hangovers A 2005 study in the British Medical Journal summarized various “remedies” and “antidotes” for hangovers and concluded that they were either placebos or worse.
Alcohol can be absorbed by the stomach and intestines, and if you drink on an empty stomach, brain activity is significantly affected within 6 minutes, and blood alcohol concentration can rush to a peak after 15 minutes. Alcohol enters the liver with the blood and is metabolized in the liver, first by an enzyme called ADH, which in turn is catalyzed by an enzyme called ALDH into acetic acid. When the acetic acid then into the tricarboxylic acid cycle into carbon dioxide and water, and only then is the completion of the great success. Generally speaking, if you drink tonight, you’ll have a hangover tomorrow and wake up the day after.
How can you drink a thousand goblets without getting drunk? The big truth is, don’t drink a thousand goblets, naturally not drunk. The second big truth is, don’t “practice drinking”. In a sense, the amount of alcohol can be said to be predestined – first of all, the genetic decision of Europeans are generally more able to drink than Asians, our ancestors used the boiling method to clean drinking water, their ancestors used the fermentation method, so the Europeans can not drink long ago died, while the ALDH enzyme deficiency of “Asian red face “still alive today. Secondly, the body weight is generally more able to drink. And the same weight to drink the same alcohol, compared to the weight of 52% is water in women, 61% of the weight is water in men’s blood alcohol peak is lower, and because women ADH enzyme is usually less, so generally men can drink more. In addition, enzyme activity decreases with age, so elders tend to drink less than in their prime.
Alcohol can irritate the stomach mucosa and make you have stomach pains, it can force the kidneys to work overtime and make you keep running to the bathroom, and it can affect the cerebellum and make you talk straight and walk straight. The most important thing is that acetaldehyde is the worst poison of all, it makes you red in the face quickly, causes many hangovers, and damages protein cell membranes plus DNA. because of the effects of acetaldehyde, drinking alcohol even in “moderation” increases the risk of breast cancer, liver cancer, and many cancers of the digestive tract. By the way, the concentration of acetaldehyde in saliva is significantly higher when you smoke while drinking.
The most effective anti-drunken trick is still to eat before drinking, and a 94-year study confirmed that mixing with food significantly slows the absorption of alcohol. If you have to pursue “everyone is down and I’m awake”, even if it doubles your body, then you can choose to enhance the activity of ADH enzyme to relieve the paralyzing effect of alcohol on the central nervous system – unfortunately, studies have found that ADH enzyme activity is directly proportional to the amount of alcohol consumed. Unfortunately, research has found that ADH enzyme activity is directly proportional to the amount of alcohol consumed, and alcoholics tend to have extremely high ADH enzyme activity, which means that the half of the “alcohol” that converts alcohol into acetaldehyde can indeed be practiced. The fructose in honey and fruit juices, as well as the caffeine in coffee and tea, can also help you “feel more awake” and thus help you drink more alcohol. As for the health risks of acetaldehyde build-up afterwards? Sorry, the “no-drink trick” won’t help.
Perhaps in the future there will really be a “non-drinking drug” that dramatically increases the activity of both enzymes. However, wearing a helmet and a heavy cotton jacket with foam wrapped around your limbs can also help reduce the death rate from a third floor jump. But the real question is, why jump from the third floor in the first place? The best antidote to alcoholism is perhaps a sobriety drug.
Tips
The so-called moderate drinking is generally 16-24 grams of alcohol a day for adult men and 8-12 grams of alcohol a day for adult women and people over 65. Look at the alcohol content on the label and figure out for yourself how much you can drink a day (high school math is useful). Children and pregnant women should refrain from drinking alcohol.
Alcohol is not the only substance that can affect human health. The byproducts of alcoholic fermentation are often more toxic, making it more difficult to get rid of a hangover. The darker the color, the more byproducts. If you have to drink, drink beer not stout, drink dry white not dry red, drink white wine vodka gin, don’t drink brandy whiskey tequila.
Drinking herbal tea while drinking is not a good idea. According to a study by Sun Yat-sen University, commercially available herbal teas of all kinds, whether it is Wang Laoji Gadobao or He Qi Zheng, almost all substantially reduced the activity of ALDH enzyme in in vitro experiments. Meaning that acetaldehyde will accumulate longer in the body. Soda and Sprite are the only candidates to increase ALDH enzyme activity in in vitro experiments, but it’s hard to say if they will still have this effect after drinking them.
The “antidotes” for hangovers that have been circulated, including vitamin B1, vitamin C, multivitamins, electrolyte drinks, and bread ……, are all inaccurate. If you get drunk once in a while, it’s okay to not eat. If you are drunk every day, it is useless to eat anything.
If you have a splitting headache from a hangover and need to recover quickly, aspirin and ibuprofen, although they can irritate the stomach mucosa, are still stronger than paracetamol (acetaminophen) which, along with alcohol, can cause liver damage.
Some drugs such as cephalosporin antibiotics inhibit ALDH enzyme activity, causing acetaldehyde to fail to metabolize into acetic acid, and taking such drugs while drinking large amounts of alcohol can be fatal. However, if you make good use of it, this drug can also be a kind of “alcohol avoidance tool”, carry a plate of drugs with you, take it out to the table before you go to the table, and then say, “I’m taking this drug, I really can’t drink”.
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