Can people with three highs, heart disease, cancer, allergies, autoimmune diseases, or pregnant women get the New Crown vaccine? (Shutterstock)
The analysis by Yuhong Dong, a European virologist and chief scientist at Biotech, is as follows.
Most of the subjects in the phase III clinical trial of the New Crown vaccine are healthy people
Unlike drugs, which are used to treat patients, vaccines are mostly administered to healthy individuals, and the focus of risk benefit assessment is different between the two. One common feature of the new crown vaccines for which phase III clinical data have been publicly published is that these studies were designed for relatively healthy populations. This is a general rule for vaccine clinical studies, as only Phase III has qualified protection rate and safety data so that further understanding of the true protection rate and safety of the vaccine for the broadest audience in a larger social population is possible after marketing.
For this reason, so-called “non-representative eligible populations” are excluded from the clinical trials of the vaccine. Individuals with immunodeficiencies, or patients with diseases such as anemia, cancer, heart disease, or stroke, are often excluded from clinical trials because their own immune status or underlying disease often affects the evaluation of the vaccine itself.
In addition, people who smoke, are alcoholics, take drugs, have large tattoos at the injection site, or have a history of allergies are often excluded.
In other words, data from phase III clinical studies of existing vaccines, both in terms of protection rates and side effects, are not necessarily applicable to these individuals.
Can people with 10 types of diseases such as triglycerides, heart disease, and allergies get the new crown vaccine?
So, how can people with underlying diseases or other special conditions determine whether they can receive the New Crown vaccine? First of all, it should be noted that each person’s physical and mental condition, type and severity of illness are different, so it is recommended to discuss with your family doctor for your own situation. The following is a list of 10 common categories of people and some suggestions for reference.
- People with high blood sugar, high blood fat and high blood pressure
The three high groups depend on the severity of the disease.
In the case of diabetic patients, for example, if the disease is relatively well controlled, such as postprandial blood sugar of 7 to 8 mmol/L, you can play; if the usual blood sugar is very high, fasting postprandial blood sugar more than 10 mmol/L, it is recommended to suspend the vaccination, and first consider the underlying disease under good control.
Patients with diabetes can get the new crown vaccine if their condition is under better control. (Shutterstock)
- Cardiovascular patients
If the heart disease is well controlled, for example, if you have not had any heart disease symptoms for several months, you can consider vaccination.
However, if you have unstable angina and have occasional attacks, or if you continue to feel weak, dizzy, or have a rapid heartbeat, the vaccine is not recommended. You should get checked to see if the heart attack has worsened or if there are precursors to a heart attack.
In addition, when the heart function is very weak, such as heart function grade 3 or 4 status, it is also recommended to control the condition first before considering vaccination.
- People who are taking medication
People who are taking medications are advised to inform their doctors of all the medications they are taking and check if there is any possible interaction between the medications and the components of the vaccine to be administered, and if so, be cautious.
This is because drug interactions are quite common and can cause some complications in terms of metabolism or immunity.
There is also the case where the vaccine side effects are similar to the drug side effects. For example, one common side effect of lipid-lowering statins is that they cause muscle pain, which is also one of the common side effects of the New Crown vaccine. If muscle pain worsens after the vaccine in people taking statins, it is not easy to distinguish whether the side effect is caused by the drug or the adverse reaction caused by the vaccine. To avoid this complication, it is advisable to consult your physician about the possibility of suspending such medications before the vaccination, or reducing the dose, or taking other treatments to control blood lipids.
Those taking medications are advised to inform their doctor of all medications they are taking and check for possible interactions between any medications and the components of the new crown vaccine that will be administered. (Shutterstock)
- Elderly people who are frail
If the frailty is due to old age, but is in good spirits, then the vaccine can be administered.
If the frailty has suddenly become weak recently and the cause cannot be found, be alert to the possibility that it is a precursor of some disease. Especially if your mental state has also deteriorated, it is best to go to the hospital first to rule out the possibility of underlying diseases and wait until your body has recovered a little before administering the vaccine.
- Cancer patients
Whether cancer patients can receive the vaccine depends on their immune system. The vaccination depends on the immune system to produce antibodies.
Cancer is divided into solid and non-solid cancers. Solid cancers such as liver cancer, stomach cancer, lung cancer and benign tumors do not affect immunity and can be considered for vaccination.
However, non-solid cancers, especially cancers of the lymphatic system, such as acute lymphoid leukemia and chronic lymphatic leukemia, directly affect the body’s immune function. Such patients have very low immunity and may not be able to produce antibodies even after vaccination, so it is recommended to wait until the condition improves and immunity is restored before going under the guidance of a doctor.
- Patients with immunodeficiency diseases
People with immunodeficiency diseases, such as those infected with AIDS, using immunosuppressants (e.g. corticosteroids) or anti-transplant rejection immunosuppressants, have very low immunity or even lost it, and cannot produce antibodies even with vaccination.
Such people are also advised not to consider vaccination for the time being, but to consider treatment of the disease first.
- Pregnant women
Pregnant women and nursing mothers are also excluded from clinical trials. To get a judgment based on clinical trial data, it is still necessary for vaccine companies to conduct follow-up clinical observation studies in this population of pregnant women.
However, in late March, the American Journal of Obstetrics and Gynecology published research showing that the mRNA vaccine is effective in pregnant and breastfeeding women. One of the researchers, Galit Alter, a professor of medicine at the Ragon Institute, said they found no evidence that pregnant and breastfeeding women had more or stronger side effects than the general population. The team noted that the levels of vaccine-induced antibodies in pregnant and lactating women were “much higher than those produced by coronavirus infection during pregnancy” compared to non-pregnant women, and that “these vaccines appear to work very effectively in these women.
- People with allergies
People with allergies are often allergic to many ingredients at once, rather than one or two, so it is best to get your body condition right before considering whether to get vaccinated.
People who have occasional allergic incidents, on the other hand, are not necessarily not eligible for vaccination. Because a person’s constitution is in dynamic change, if you were allergic to a certain drug or food or to a mosquito bite a few years ago, but your immune system is not necessarily still in an allergic state now, it does not mean that your immune system will definitely be allergic to the current vaccine components. Therefore, it is recommended to discuss and consult with your doctor before deciding whether to give the injection and which vaccine to give.
People who have occasional allergic events should not necessarily not be vaccinated. (Shutterstock)
- People who have been infected with the new coronavirus
People who are already infected with the new coronavirus may already have antibodies in their bodies, but it’s just a matter of whether they have high or low titers. A recent study in the New England Journal of Medicine showed that people infected with New Coronavirus produced higher levels of various antibodies, especially neutralizing antibodies (neutralizing antibodies are antibodies that bind directly to the virus and protect a person from infection) than people who had not received the mRNA vaccine three weeks after a single dose.
The study, published in the journal Nature Medicine in April, showed that one dose of the vaccine produced the same effect in people who were already infected with the new crown as two doses in the general population. However, U.S. officials say that two doses of the vaccine are still required, whether or not one has been infected.
However, people who are in the acute stage of neocon infection should wait until the symptoms of infection have returned and the quarantine period is over before considering administering the vaccine.
- People who have already received other vaccines
Some people ask: Will there be any conflict between the mRNA vaccine and the inactivated vaccine such as Coxin vaccine?
Currently, there are no clinical studies on mixing all vaccines. Oxford University is conducting a clinical trial to explore whether the first dose of mRNA vaccine, followed by a second dose of adenovirus vector vaccine, is better and more durable than vaccination alone. However, until data from the clinical study is available, we are cautious about mixing vaccines and recommend that the full course of vaccination be completed with the same vaccine if possible.
These two groups of people are not allowed to receive the new crown vaccine
So, who are the people who are clearly not allowed to get the vaccine? Both the CDC (Centers for Disease Control and Prevention) and the various vaccine manufacturers state that there are two groups of people who are prohibited from receiving the Neocon vaccine.
Two groups of people are prohibited from getting the New Crown vaccine, including people with severe allergies to the vaccine’s ingredients.
People with a known severe or immediate allergy to any of the vaccine’s components are not allowed to receive the new vaccine.
- People who have severe or immediate allergic reactions after the first dose should not receive a second dose.
Why is vaccination particularly contraindicated for allergies?
Acute allergic reactions can be life-threatening and occur quickly, and can take away life within a few hours or even ten minutes. Therefore, once an acute allergic reaction occurs, you should immediately call an emergency vehicle to send you to a doctor.
So, how do I know if I am allergic to the ingredients in a vaccine?
No matter what kind of vaccine you get, there is an instruction manual in the package, and usually the various ingredients of the vaccine are clearly listed on the first page, so read it carefully after you get the vaccine, and if you have any questions that you don’t understand, don’t hesitate to consult your doctor or local health department.
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